Avastin is the brand name for Bevacizumab, a drug originally developed and approved by the FDA for treating various cancers. It works by blocking vascular endothelial growth factor (VEGF)-a protein responsible for the growth of abnormal blood vessels. In ophthalmology, Avastin is used off-label to treat several serious eye conditions.
When injected into the eye (called an intravitreal Avastin injection), Avastin inhibits VEGF and prevents the formation and leakage of abnormal blood vessels at the back of the eye. These vessels can cause swelling, bleeding, and ultimately vision loss if left untreated.
Avastin (Bevacizumab) is a monoclonal antibody that binds to VEGF, preventing it from attaching to blood vessel receptors. This stops the VEGF from stimulating the growth of abnormal vessels and reduces leakage and swelling in the retina. This mechanism is crucial in treating diseases where fluid buildup or abnormal vessel growth damages the macula and impairs vision.
The Avastin injection procedure is performed under sterile conditions, similar to a minor surgical setup:
After the injection:
The Avastin injection price in India is approximately ₹15,000 – ₹25,000 per dose when administered in a sterile operation theatre. This cost includes:
| Drug | Type | Duration | Approx. Cost | FDA Approved for Eye Use |
| Avastin | Anti-VEGF | 4–6 weeks | ₹15,000 – ₹25,000 | Off-label |
| Accentrix | Anti-VEGF (Ranibizumab) | 4–6 week | ₹35,000–₹65,000 | Yes |
| Ozurdex | Steroid Implant | 4–6 months | ₹40,000–₹70,000 | Yes |
Note: Avastin remains the most cost-effective anti-VEGF option, especially for patients needing multiple injections.
| Feature | Avastin | Accentrix (Ranibizumab) | Ozurdex (Dexamethasone) |
| Drug Type | Anti-VEGF (whole antibody) | Anti-VEGF (antibody fragment) | Steroid Implant |
| FDA Approval for Eye | No (off-label use) | Yes | Yes |
| Duration of Effect | 4–6 weeks | 4–6 weeks | 4–6 months |
| Common Use | Wet ARMD, DME, RVO | Wet ARMD, DME, RVO | DME, RVO (not Wet ARMD) |
| Cost | ₹15,000- ₹25,000 | ₹35,000–₹65,000 | ₹40,000–₹70,000 |
| Risk of Infection | Slightly higher (multi-use vial) | Low (single-use vial) | Moderate (due to steroid use) |
| Side Effects | Mild | Mild | Cataract, Raised IOP |
Patients with:
The standard Avastin injection dose for the eye is:
Yes. Treatment usually begins with:
Some patients may require:
Most common side effects include:
Red Flag Symptoms (Call your doctor immediately):
After receiving the Avastin eye injection:
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Avastin is used for treating retinal diseases like wet macular degeneration, diabetic retinopathy, macular edema, and retinal vein occlusion
Avastin is a VEGF-blocking drug used to stop the growth of abnormal blood vessels in the eye. It is administered via an intravitreal injection.
The Avastin injection cost in India ranges around ₹15,000 – ₹25,000 per dose, including all procedure-related expenses.
Yes. Avastin is commonly used off-label to treat diabetic macular edema and proliferative diabetic retinopathy with proven safety and effectiveness.
Initially, 3 injections are given monthly. Based on response, you may need more on a monthly or as-needed basis.
Most side effects are mild (redness, floaters), but rare complications like infection or retinal detachment can occur.
It’s best to avoid driving on the day of the injection, as vision might be temporarily blurry and the eye may feel irritated.
Vision may start improving within a few weeks, often noticeable after the first 2–3 injections depending on the condition being treated.
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