What is Ozurdex injection?
Ozurdex is an intravitreal sustained release Dexamethasone (0.7mg) Implant. Dexamethasone is a steroid. It is injected into the eye to treat Macular edema.
What is Macular edema ?
Macular edema is swelling or collection of fluid in the central part of the retina. The fluid collection occurs due to 2 main reasons :
Vascular component – Due to release of VEGF by the diseased retina. This effect of VEGF is counteracted by anti VEGF drugs like Accentrix, Avastin, and Eylea.
Inflammatory component – The diseased retina also releases different inflammatory mediators, which contribute to the swelling. This inflammatory component is treated by giving intravitreal steroids like ozurdex injections.
These processes occur in primary inflammatory diseases like uveitis, or primarily vascular diseases like diabetic macular edema and retinal vein occlusions.
How does Ozurdex help in Macular edema ?
Ozurdex is a corticosteroid, and works to help reduce the inflammation in the retina. Ozurdex helps by improving visual acuity. Once injected, the implant dissolves slowly and releases a corticosteroid called dexamethasone. Corticosteroids, such as dexamethasone, reduce inflammation
Preparing for the taking the ozurdex eye injection
Speak with your doctor about any questions/concerns you may have. Arrange to have somebody take you to and from your appointment. Create a list of all the prescription and over-the-counter medications you take.
How is Ozurdex given ?
The injection of Ozurdex will only take a few moments. You will be awake. Your doctor will clean and numb the surface of the eye. Your doctor will inject Ozurdex using a special applicator that’s about the size of a pen. During the injection you may feel pressure. You may then hear a click when your doctor presses the button that releases the Ozurdex implant in your eye. Your doctor will check your eye, and then you will be ready to go home. Your eye will be patched, and you can remove the eye pad after you reach home. You will be required to put antibiotic eye drops for 5 days after the procedure to prevent infection.
Over time, you should notice an improvement in your vision as the swelling reduces. However, individual results may vary.
Does the implant need to be removed ?
Ozurdex implant will dissolve over months and will not need to be removed
What are the precautions to take after injection ?
You will be given antibiotic drops to use for 5 days after the injection, to ensure that no infection occurs.
Avoid rubbing your eyes after the injection. You can wash your face the following day, but avoid swimming for few days after injection.
If your eye becomes red, sensitive to light, painful, or develops a change in vision, please contact your eye doctor immediately
When should Ozurdex be avoided ?
Ozurdex should not be used if you have any infections in or around the eyes, including most viral diseases of the cornea and conjunctiva, including active herpes viral infection of the eye, mycobacterial infections, and fungal diseases.
Ozurdex should not be used if you have glaucoma that has progressed to a cup-to-disc ratio of greater than 0.8.
Ozurdex should not be used if you have a posterior lens capsule that is torn or ruptured.
Ozurdex should not be used if you are allergic to any of its ingredients.
Are there any side effects after taking Ozurdex Injection ?
Increased eye pressure
There is a chance of an increase in eye pressure that generally returns to where it started. If you experience this, you will be observed by your doctor to determine the need for the eye pressure to be managed with eye drops
Cataract is a condition in which the lens of the eye becomes cloudy or opaque. It’s possible a cataract could form if you have repeated treatments with Ozurdex. If that happens, your vision may decrease, and you will need an operation to remove the cataract and restore your vision
What is the advantage of Ozurdex eye injection ?
Ozurdex is a sustained release steroid. It means that the steroid is slowly released from the injected capsule into the eye. Thus, there is no need to take monthly injections. This one injection may last for upto 3-4 months.
What is the Ozurdex eye injection cost in India ?
The Ozurdex eye injection cost in India is currently 22000. We charge 13000 extra over and above this, which includes the operation theatre, surgeon fees and other consumables cost. The cost to the patient will be Rs 35000 per injection.